Nicolas Monney

Applications Specialist
Mettler-Toledo Analytical GmbH

Switzerland

2024 Presentation

Water is a key component in any food or dietary product. Its amount must be closely monitored to ensure the stable quality of the products and to prevent premature spoiling due to excessive moisture content. Various methods exist to measure the moisture or water content in a product, including the loss on drying method and Karl Fischer titration.

The major challenge with moisture or water analysis is the proper extraction of water from the sample. Depending on the nature of the sample, one technique may be more suitable than the other.

In this presentation, we will explore the main differences between moisture and water analysis and describe the various solutions provided by Mettler Toledo. These solutions include different water extraction techniques that can be employed on different types of instruments.

With the proper technique and instrument, you will be able to determine the moisture or water content of your samples precisely. This ensures consistent quality and shelf life of your products, ultimately benefiting both producers and consumers.

Water is a key parameter that must be closely monitored for all active pharmaceutical ingredients (APIs) and final products to ensure compliance and maintain their shelf-life. One of the most widespread methods for measuring water content is Karl Fischer titration, which is specific to water. However, it can be challenging to extract water from samples, and the process requires significant manipulation from the operator, making it time-consuming and prone to errors.

In this presentation, we will discuss the challenges associated with water extraction and sample manipulation, and we will describe all the solutions that Mettler Toledo can provide. These solutions include various water extraction techniques and the use of an automatic oven sample changer. By employing these methodologies, we can significantly reduce manual intervention and improve the accuracy of the water content determination.

About the speaker:

Nicolas Monney holds a Ph.D. in Physical Chemistry. His research focused on studying electron transfer through proteins using low-temperature spectroscopy and ab-initio simulations.

Nicolas began his career at Mettler Toledo nearly ten years ago, taking on the role of Applications Specialist for Titration. In this role, he develops innovative titration applications and collaborates closely with the R&D department to facilitate the development of new products.

Additionally, he provides second-level support for the sales force of Mettler Toledo and its partners on titration projects worldwide. His responsibilities also include delivering comprehensive on-site and online training sessions and presentations.